Desmoglein-1 (DSG1) Antibody MBS439914 from MyBioSource.com

Product Specs
ItemDesmoglein-1 (DSG1) Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS439914
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ReactivityHuman. Others not known
TargetDesmoglein-1 (DSG1)
IsotypeIgG1 kappa
Molecular Weight150kDa (precursor); 160kDa (mature)
CloneDSG1/1733
HostMouse
ImmunogenRecognizes a protein of ~150kDa, identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity
NCBI Full Gene Namedesmoglein 1
NCBI Gene AliasesPPKS1, SPPK1, EPKHIA, CDHF4, DG1, DSG, EPKHE
ClonalityMonoclonal